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How faecal transplants may increase most cancers remedies


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TEM images of the full motor assembly with attached rotor arm

The motors are constructed from DNA strands organized into triangular platforms hooked up to an extended, rotating arm.Credit score: A.-Okay. Pumm et al./Nature (CC BY 4.0)

Physicists have constructed a molecular-scale motor totally from DNA strands, and used it to retailer vitality by winding up a DNA ‘spring’. It isn’t the primary DNA nanomotor, however it’s “definitely the primary one to truly carry out measurable mechanical work”, says biophysicist and co-author Hendrik Dietz. The tiny machine features vitality from Brownian movement — the fixed random argy-bargy of molecules in a medium. The machine turns just like the ratchet wheel in a clock, winding a string of DNA like a spiral spring.

Nature | 4 min learn

See extra: A 3-minute video introduces DNA origami — the artwork of folding DNA to create tiny nanoscale machines that might work contained in the human physique. (Nature, from 2016)

Reference: Nature paper

Emissions information for various areas may assist researchers to scale back the environmental price of synthetic intelligence (AI) experiments. For instance, a machine-learning mannequin skilled within the central United States or Germany emitted greater than twice as a lot carbon dioxide as the identical mannequin skilled in Norway, which will get most of its electrical energy from hydroelectric energy, or France, which depends totally on nuclear energy.

Nature | 5 min learn

Reference: arXiv preprint (not peer reviewed)

AI’s carbon footprint: Line chart showing the emissions of language-learning model BERT over one year at various locations.

Supply: Ref. 1

A quiet epidemic has been spreading amongst ladies and ladies throughout Afghanistan since a minimum of 2004, and case numbers have risen additional for the reason that Taliban took energy in August 2021. Native media experiences, authorities officers and the ladies themselves blame these occasions — which typically strike many individuals without delay — to poisonings, typically by Taliban or different militant teams. Medical doctors have identified the sickness as conversion dysfunction, during which bodily signs mimic a neurological dysfunction and infrequently observe a interval of great emotional or bodily misery. In 2021, the ladies’s psychiatric ward of Herat Regional Hospital recorded 12,678 instances of the mysterious ailment, typically leading to lack of consciousness and paralysis. Medical research of the situation are extraordinarily uncommon.

Undark | 14 min learn

Options & opinion

Zion Levi’s melanoma went into remission because of a robust immunotherapy drug referred to as nivolumab. Then he donated his faeces — and the microbes inside — to assist others who had failed to reply to the therapy or whose cancers had turn out to be resistant to it. It was a small trial — it concerned solely 26 individuals — however one in three of them benefited from the faecal microbial switch (FMT). Right this moment, a minimum of 30 FMT trials are underneath means world wide. They trace at a brand new period of ‘ecological oncology’ and goal to uncover how the intestine microbiome influences the development of distant tumours, the effectiveness of remedies and the organisms that reside in tumours themselves.

Nature | 13 min learn

Reference: Science paper 1 & Science paper 2

When Jessica Eise requested espresso farmers in Colombia what they needed from local weather science, they requested sensible and actionable data: the best way to fend off rising pests and ailments, for instance, or higher predict optimum harvest time. Eise and her workforce went to the literature, however discovered little in the best way of simple ideas for adapting to a shifting local weather. The expertise made her suppose: “If all of the analysis will not be serving to those that want it most, what’s the level?” Eise urges fellow students to turn out to be extra engaged with real-world wants and suggests six methods to assist make it occur.

Nature | 6 min learn

Engineer Greg Robinson is a long-serving NASA supervisor who many credit score for saving the deeply troubled James Webb Area Telescope. NASA leaders needed to “twist each of my arms” to persuade him to tackle the venture, jokes Robinson. However Webb wanted his mastery of technical element and bureaucratic nuance. It was years late and billions over price range. It’s fiendishly difficult, has nearly no margin for error and has a whole bunch of single factors of failure. Now, because of Robinson — and the remainder of the sensible Webb workforce — the telescope is shaping as much as be one of many house company’s biggest triumphs.

The Wall Road Journal | 8 min learn & The New York Instances | 7 min learn

See extra: Robinson joined the enjoyable on the discuss present “The Every day Present with Trevor Noah” on Tuesday (YouTube | 10 min video)

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